Analysis of Dose-Response Curves for the In Vitro Susceptibility of Plasmodium Falciparum to Antimalarials using a Pocket Computer
- 1 January 1988
- journal article
- research article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 38 (1) , 15-18
- https://doi.org/10.4269/ajtmh.1988.38.15
Abstract
A small pocket computer, Sharp PC-1500, was programmed to analyze the dose-response curves generated by the in vitro assay of antimalarials against field isolates of Plasmodium falciparum. Using nonlinear regression the analysis provided an estimate of the 50% inhibitory concentration with 95% confidence limits and a graph of the data points and regression function line. The pocket computer with the nonlinear regression program offers a powerful, portable, and inexpensive data analysis system suitable for field use.This publication has 1 reference indexed in Scilit:
- Evaluation of an In Vitro Assay System for Drug Susceptibility of Field Isolates of Plasmodium Falciparum from Southern ThailandThe American Journal of Tropical Medicine and Hygiene, 1988