Presenilin 1 Is Required for Maturation and Cell Surface Accumulation of Nicastrin
Open Access
- 1 May 2002
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 277 (21) , 19236-19240
- https://doi.org/10.1074/jbc.c200148200
Abstract
No abstract availableKeywords
This publication has 29 references indexed in Scilit:
- Activity-dependent isolation of the presenilin– γ-secretase complex reveals nicastrin and a γ substrateProceedings of the National Academy of Sciences, 2002
- Transition-state analogue inhibitors of γ-secretase bind directly to presenilin-1Nature Cell Biology, 2000
- Photoactivated γ-secretase inhibitors directed to the active site covalently label presenilin 1Nature, 2000
- Presenilin 1 is linked with γ-secretase activity in the detergent solubilized stateProceedings of the National Academy of Sciences, 2000
- Molecular genetics of Alzheimer’s diseaseBiological Psychiatry, 2000
- Effects of PS1 Deficiency on Membrane Protein Trafficking in NeuronsNeuron, 1998
- Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor proteinNature, 1998
- Accelerated Amyloid Deposition in the Brains of Transgenic Mice Coexpressing Mutant Presenilin 1 and Amyloid Precursor ProteinsNeuron, 1997
- Amyloid β-Protein and the Genetics of Alzheimer's DiseaseJournal of Biological Chemistry, 1996
- Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's diseaseNature Medicine, 1996