Effects of hypocapnia and hypercapnia on myocardial contractility
- 1 December 1960
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 199 (6) , 1121-1124
- https://doi.org/10.1152/ajplegacy.1960.199.6.1121
Abstract
Moderate elevations of pCO2 (61–75 mm Hg) did not consistently depress myocardial contractility as determined by standard ventricular function curves. With an altered preparation in which heart rate and left atrial pressure were held constant, a pCO2 of 60–75 mm Hg was accompanied by an average reduction in stroke work to 73.6% of its control value, while hypocapnia with an alveolar pCO2 of 6–13 mm Hg was unaccompanied by any consistent reduction in stroke work.Keywords
This publication has 4 references indexed in Scilit:
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- Circulation in Dogs After Respiratory Arrest Induced by CurareJournal of Applied Physiology, 1956
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- Effect of Carbon Dioxide Excess on Contractile Force of Heart, In SituAmerican Journal of Physiology-Legacy Content, 1953