Blood-Group A and the Related Glycolipids of Human Lung12
- 1 February 1982
- journal article
- research article
- Published by Oxford University Press (OUP) in The Journal of Biochemistry
- Vol. 91 (2) , 627-632
- https://doi.org/10.1093/oxfordjournals.jbchem.a133734
Abstract
Three glucosamine-containing sphingoglycolipids were isolated from human lung tissue of a blood group-A subject. They were hexaglycosyl, pentaglycosyl, and tetraglycosyl ceramides. The hexaglycosyl ceramide exhibited blood group-A anti-genicity, and the following chemical structure was proposed on the basis of sequential glycosidase treatment and methylation analysis. The pentaglycosyl ceramide from human lung was a blood group H(O)-active glycolipid having a carbohydrate composition of Fuc:GlcNAc:Gal:Glc (1:1:2:1). The tetraglycosyl ceramide is probably paragloboside (lactoneotetraosyl ceramide).Keywords
This publication has 2 references indexed in Scilit:
- FUCOLIPIDS1978
- The isolation and partial characterisation of the glycolipids from pig lungBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1966