Farnesoid X Receptor, through the Binding with Steroidogenic Factor 1-responsive Element, Inhibits Aromatase Expression in Tumor Leydig Cells
Open Access
- 1 February 2010
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 285 (8) , 5581-5593
- https://doi.org/10.1074/jbc.m109.052670
Abstract
No abstract availableKeywords
This publication has 57 references indexed in Scilit:
- Bile acids and signal transduction: Role in glucose homeostasisCellular Signalling, 2008
- Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cellsBiochemical Journal, 2008
- Insulin-Like Growth Factor-I, Regulating Aromatase Expression through Steroidogenic Factor 1, Supports Estrogen-Dependent Tumor Leydig Cell ProliferationCancer Research, 2007
- Farnesol, a mevalonate pathway intermediate, stimulates MCF-7 breast cancer cell growth through farnesoid-X-receptor-mediated estrogen receptor activationBreast Cancer Research and Treatment, 2007
- The small heterodimer partner is a gonadal gatekeeper of sexual maturation in male miceGenes & Development, 2007
- FXR, a multipurpose nuclear receptorTrends in Biochemical Sciences, 2006
- Nuclear bile acid receptor FXR as pharmacological target: Are we there yet?FEBS Letters, 2006
- Identification of the DNA Binding Specificity and Potential Target Genes for the Farnesoid X-activated ReceptorJournal of Biological Chemistry, 2000
- Steroidogenic Factor 1-Dependent Promoter Activity of the Human Steroidogenic Acute Regulatory Protein (StAR) GeneBiochemistry, 1996
- Human testicular aromatase: immunocytochemical and biochemical studiesJournal of Clinical Endocrinology & Metabolism, 1995