Interferon-alpha therapy in atopic dermatitis.
Open Access
- 1 September 1992
- journal article
- Published by Medical Journals Sweden AB in Acta Dermato-Venereologica
- Vol. 72 (5) , 370-372
- https://doi.org/10.2340/0001555572370372
Abstract
Thirteen patients with a severe adult form of atopic dermatitis (AD) received 3.0 x 10(6) IU of recombinant interferon-alpha 2a (rIFN-alpha 2a) 3 times a week. A satisfactory response was obtained in 5 of them. Serum IgE levels in all 13 patients remained unchanged throughout the study. Flu-like symptoms were common, but clinical or laboratory adverse effects were otherwise slight. The moderately beneficial therapeutic effects observed in this study support a possible role for IFN-alpha in controlling immunologic deficiencies in atopic dermatitis.Keywords
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