Manchester and Oxford Universities Scale for the Psychopathological Assessment of Dementia (MOUSEPAD)

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Abstract
Background: There is increasing awareness of the importance of psychopathological and behavioural changes in dementia and a need for an instrument to measure these features which achieves an appropriate compromise between brevity and breadth. We describe a newly developed 59-item instrument: the MOUSEPAD.Method: Reliability, sensitivity and validity were examined with 30 carers, each of whom was interviewed four times over six weeks.Results: For different symptom groups, kappa ranged from 0.43 to 0.93 for test–retest reliability, from 0.56 to 1.0 for inter-rater reliability, and from 0.43 to 0.67 for the validation study.Conclusions: The scale may be useful as an outcome measure in drug trials, for correlating psychopathological and behavioural changes with post-mortem findings, and in epidemiological surveys.