Complexes of anti‐prothrombin antibodies and prothrombin cause lupus anticoagulant activity by competing with the binding of clotting factors for catalytic phospholipid surfaces
Open Access
- 1 June 2001
- journal article
- research article
- Published by Wiley in British Journal of Haematology
- Vol. 113 (3) , 621-629
- https://doi.org/10.1046/j.1365-2141.2001.02755.x
Abstract
The British Journal of Haematology publishes original research papers in clinical, laboratory and experimental haematology. The Journal also features annotations, reviews, short reports, images in haematology and Letters to the Editor.Keywords
This publication has 32 references indexed in Scilit:
- Anti-beta2-glycoprotein I (beta2GPI) monoclonal antibodies with lupus anticoagulant-like activity enhance the beta2GPI binding to phospholipids.Journal of Clinical Investigation, 1997
- Role of Divalency in the High-Affinity Binding of Anticardiolipin Antibody−β2-Glycoprotein I Complexes to Lipid MembranesBiochemistry, 1996
- Inhibition of prothrombin activation by antiphospholipid antibodies and β2‐glycoprotein 1British Journal of Haematology, 1994
- Lupus anticoagulant activity of autoimmune antiphospholipid antibodies is dependent upon beta 2-glycoprotein I.Journal of Clinical Investigation, 1992
- Inhibition of activated protein C and its cofactor protein S by antiphospholipid antibodiesBritish Journal of Haematology, 1990
- Anticardiolipin antibodies (ACA) directed not to cardiolipin but to a plasma protein cofactorThe Lancet, 1990
- Inactivation of human factor VIII by activated protein C. Cofactor activity of protein S and protective effect of von Willebrand factor.Journal of Clinical Investigation, 1988
- Coagulation screen is more specific than the anticardiolipin antibody ELISA in defining a thrombotic subset of lupus patients.Annals of the Rheumatic Diseases, 1988
- Single bilayer vesicles prepared without sonication physico-chemical propertiesBiochimica et Biophysica Acta (BBA) - Biomembranes, 1976
- THROMBOTEST A NEW METHOD FOR CONTROLLING ANTICOAGULANT THERAPYThe Lancet, 1959