Disappearance Rate of Exogenous Insulin, Insulin Sensitivity, Responses of Plasma Growth Hormone and Cortisol and Urinary Epinephrine to Hypoglycemia in Prediabetic Subjects
- 1 January 1969
- journal article
- research article
- Published by Georg Thieme Verlag KG in Hormone and Metabolic Research
- Vol. 1 (05) , 221-223
- https://doi.org/10.1055/s-0028-1095138
Abstract
Insulin sensitivity was found to be increased in a group of nine prediabetic subjects, indicating that some mechanism(s) compensates for the decreased ability to secrete insulin in response to glucose. Diabetes probably develops in prediabetic subjects when such a compensation is lost. The disappearance rate of insulin was of identical magnitude in the prediabetic and normal groups, indicating that the lower plasma insulin values in prediabetes do reflect a decreased secretion of insulin. No difference was found between the two groups regarding the responses of HGH, Cortisol and epinephrine to hypoglycemia.Keywords
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