An edeine resistant mRNA‐dependent protein synthesis system from a Saccharomyces cerevisiae mutant
- 20 August 1984
- journal article
- Published by Wiley in FEBS Letters
- Vol. 174 (1) , 47-49
- https://doi.org/10.1016/0014-5793(84)81075-3
Abstract
A cell‐free protein synthesizing system from a mutant of Saccharomyces cerevisiae translated exogenous mRNA in the presence of 2μM edeine, while a similar system from wild‐type strain was completely inhibited by the drug. The mutant ribosomes showed an affinity for [125I]edeine comparable to the wild‐type ribosomes, thereby suggesting that these macromolecules alone were not responsible for the edeine‐resistant capacity of the mutant.Keywords
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