A Subset of Viral Transcripts Packaged Within Human Cytomegalovirus Particles
- 30 June 2000
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 288 (5475) , 2373-2376
- https://doi.org/10.1126/science.288.5475.2373
Abstract
A human cytomegalovirus gene array was used to identify a previously unidentified class of viral transcripts. These transcripts, termed virion RNAs, were packaged within infectious virions and were delivered to the host cell on infection. This mechanism of herpesvirus gene expression allows for viral genes to be expressed within an infected cell immediately after virus entry and in the absence of transcription from the viral genome.Keywords
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