Abstract
Although rabies in Africa is relatively insignificant in terms of human mortality, the disease is still relevant because of the high costs of rabies prevention. Over the past 2 decades, demographic, economic and sociopolitical trends in Africa have increasingly favoured the persistence and spread of rabies, while limiting the effectiveness of control measures. Dog rabies predominates throughout most of Africa; the domestic dog is the principal reservoir host as well as the most important source of infection for people. However, wildlife rabies is increasingly a concern, both as a threat to endangered wildlife populations and because of the possible emergence of new maintenance hosts.