Prenatal Exposure to Prednisone in Humans and Animals Retards Intrauterine Growth
- 27 October 1978
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 202 (4366) , 436-438
- https://doi.org/10.1126/science.705336
Abstract
Prednisone treatment for infertility and subsequent pregnancy maintenance in humans resulted in a significant decrease in the birth weight of full-term infants and a marked increase in the percentage of newborn infants weighing 2500 grams or less, that is, "light for dates" in comparison to control offspring. A parallel experiment with mice indicated that the reduction of birth weight was caused by exposure to corticosteroids rather than to maternal disease or malfunction.This publication has 25 references indexed in Scilit:
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