Concise synthesis of CC-1065/duocarmycin pharmacophore using the intramolecular Heck reaction
- 1 January 1993
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 17,p. 1941-1942
- https://doi.org/10.1039/p19930001941
Abstract
3-Methyleneindoline derivatives were synthesized by intramolecular Heck reaction of N-allyl-2-iodoaniline derivatives in the presence of Ag2Co3. This method was successfully applied to the synthesis of the CC-1065/duocarmycin pharmacophore.Keywords
This publication has 0 references indexed in Scilit: