Comparative statistics for DNA and protein sequences: single sequence analysis.
- 1 September 1985
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 82 (17) , 5800-5804
- https://doi.org/10.1073/pnas.82.17.5800
Abstract
Four categories of data representations are used to help interpret structures and similarities of nucleic acid and protein sequences. Statistical significance of the observed relationships revealed by these representations are assessed by a hierarchy of permutation procedures and by comparisons with theoretical random models. Applications are presented for various DNA sequences including papovaviruses, Epstein-Barr virus, mitochondrial genomes, and several globin and immunoglobulin genes.This publication has 11 references indexed in Scilit:
- Evidence for higher rates of nucleotide substitution in rodents than in man.Proceedings of the National Academy of Sciences, 1985
- Unusual regulation of simian virus 40 early-region transcription in genomes containing two origins of DNA replication.Molecular and Cellular Biology, 1984
- DNA sequence and expression of the B95-8 Epstein—Barr virus genomeNature, 1984
- PERMUTATION METHODS FOR THE STRUCTURED EXPLORATORY DATA-ANALYSIS (SEDA) OF FAMILIAL TRAIT VALUES1984
- Complete nucleotide sequence of bacteriophage T7 DNA and the locations of T7 genetic elementsJournal of Molecular Biology, 1983
- Statistical characterization of nucleic acid sequence functional domainsNucleic Acids Research, 1983
- Random sequencesJournal of Molecular Biology, 1983
- Organization of the Epstein-Barr virus DNA molecule. II. Fine mapping of the boundaries of the internal repeat cluster of B95-8 and identification of additional small tandem repeats adjacent to the HR-1 deletionJournal of Virology, 1982
- Similar Amino Acid Sequences: Chance or Common Ancestry?Science, 1981