Factors Related to Outcome after Pneumonectomy: Retrospective Study of 62 Patients

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Abstract
To find out which risk factors affect outcome after pneumonectomy. Retrospective study. Teaching hospital, The Netherlands. 62 patients who were treated for bronchial cancer by pneumonectomy between 1984 and 1995. Hospital mortality and postoperative complications. Hospital mortality increased with age, being 5/51 (10%) in the 40-69 age group and 4/11 (36%) in patients aged 70 or more. In the American Society of Anesthesiologists (ASA) class I group hospital mortality was 8% (2/26), in class II 12% (3/26) and in class III 40% (4/10). Hospital mortality was highest when the FEV1:FVC-ratio was below 55%. Cardiac arrhythmias developed in 8 (13%), early bronchopleural fistulas in 7 (11%), and postpneumonectomy syndrome in 5 (8%). These major complications had a high mortality. Respiratory function, ASA class, and age over 70 years are the main prognostic factors for hospital morbidity and mortality after pneumonectomy.

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