CEREBROSPINAL FLUID γ‐GLOBULINS IN SUBACUTE SCLEROSING LEUCOENCEPHALITIS

Abstract
— Immunoelectrophoretis, gel filtration-electrophoresis and immuno-gel filtration of cerebral fluid samples obtained from five patients with subacute sclerosing leucoencephalitis and known to contain an abnormal γ-globulin fraction (γe) produced strong evidence that the γc-globulin is made up of several components of small molecular size. This fraction is obviously not homogeneous, since some of the cases show more than one precipitate on immuno-gel filtration with immune serum against γ-globulin. The γc appears to be closely related to the Fab-fragment of human γ-globulin.