New approach to aminoglycoside antibiotics
- 1 January 1980
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 20,p. 944-945
- https://doi.org/10.1039/c39800000944
Abstract
Photobromination of peracylated hexopyranoses and treatment of the resultant 5-bromo-derivatives with zinc and acetic acid afforded 6-deoxy-5-enose esters which, with mercury(II) salts in aqueous media, gave 2-deoxyinosose triesters; applied to β-D-maltose octa-acetate, these procedures afforded an α-glucosylated inosose derivative which on further α-glycosylation gave a ‘pseudotrisac-charide’ related to those upon which aminoglycoside antibiotics are based.Keywords
This publication has 0 references indexed in Scilit: