Linkage of autosomal dominant dystrophic epidermolysis bullosa in three British families to the marker D3S2 close to the COL7A1 locus.
Open Access
- 1 June 1992
- journal article
- research article
- Published by BMJ in Journal of Medical Genetics
- Vol. 29 (6) , 381-382
- https://doi.org/10.1136/jmg.29.6.381
Abstract
Linkage of the anonymous marker D3S2 at 3p21 has been shown in three British families with dominant dystrophic epidermolysis bullosa with a combined lod score of 6.75 at theta = 0. This locus is close to the collagen type VII locus implying that abnormalities of this gene cause dominant dystrophic epidermolysis bullosa.Keywords
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