Asymmetric Synthesis of α-Amino Phosphonic Acids Employing the Condensation of Nitrones with Phosphite Derivatives

Abstract
Chiral α-amino phosphonic acid derivatives were synthesized by condensing an enantiomerically homogeneous diazasilyl phosphite with a series of prochiral nitrones. The reactions proceed under mild conditions with moderate to high enantioselectivities and good yields.

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