SERUM IMMUNOGLOBULIN-A IN CHRONIC BRONCHIAL INFLAMMATION

  • 1 January 1977
    • journal article
    • research article
    • Vol. 58  (1) , 33-40
Abstract
Serum Ig[immunoglobulin]A was determined by the single radial immunodiffusion method in specimens collected during 1 yr from 178 patients suffering from chronic bronchitis syndrome. The IgA level was permanently, significantly higher in the group of patients than in the group of healthy controls. The difference between the patients and controls increased until middle age. This phenomenon was parallel with an aggravation of the average functional severity of the pulmonary disease. Despite the continued aggravation, the difference lessened after the age of 49. Three cases of severe quantitative IgA abnormality were detected among the patients: 1 case of IgA myeloma and 2 cases of almost total IgA deficiency. One of the latter also showed IgE deficiency.

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