Ultrastructural Changes in the Mucosa of the Small Intestine in Patients with Geophagia (Prasadʼs Syndrome)

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Abstract
The ultrastructure of intestinal mucosa in two geophagia patients with growth retardation, hypogonadism, hepatosplenomegaly, zinc deficiency, iron deficiency, and anemia was studied with an electron microscope. Alterations in the ultrastructure of intestinal mucosa, especially in Paneth's cells, possibly due to zinc deficiency were observed.