Biosynthesis of valanimycin.
- 1 January 1986
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 39 (9) , 1263-1269
- https://doi.org/10.7164/antibiotics.39.1263
Abstract
In the biosynthesis of valanimycin, valine is mostly incorporated into the isobutyl moiety of the antibiotic. The .alpha.-substituted acrylic moiety of valanimycin is derived from alanine. However, a part of alanine is metabolized into valine, thus incorporated also into the isobutyl moiety. Anaerobic conditions and some reducing agents strongly inhibit the biosynthesis.This publication has 2 references indexed in Scilit:
- Isolation and properties of valanimycin, a new azoxy antibiotic.The Journal of Antibiotics, 1986
- Biosynthesis of 7‐chloro‐6‐demethyltetracycline in the presence of certain homocysteine derivatives and methoxinineBiotechnology & Bioengineering, 1963