Production a corpus luteum angiogenic factor responsible for proliferation of capillaries and neovascularization of the corpus luteum.

Publisher Website
Google Scholar
Abstract
Factors controlling changes in the vascular pattern of the ovary that occur during the reproductive cycle were investigated. By using the rabbit cornea, abilities of ovarian corpus luteum and of follicles to induce neovascularization were compared. While the corpus luteum was capable of inducing neovascularization, the follicles did not have this ability. Apparently the corpus luteum actively participates in its own neovascularization by secreting a factor that we have called corpus luteum angiogenic factor (CLAF).