The Healthy People 2000 objective to reduce the prevalence of cigarette smoking among adults to no more than 15% is unlikely to be achieved in Florida1 or in the United States2,3 by the end of this year. In the 1990s, well-funded, coordinated programs to prevent and reduce youth and/or adult tobacco use have been implemented in California,4 Massachusetts,5 Oregon,6 and Florida.7 Since the completion of the Master Settlement Agreement between state attorneys general and the tobacco industry, many more states are currently developing tobacco use prevention and reduction programs.8 To achieve a reduction in youth and adult tobacco use, initiation of tobacco use by children, adolescents, and young adults must decline, and cessation efforts among current smokers must be successful.9,10 Because tobacco use often begins in adolescence and cessation is difficult once regular use is established,11 interventions to prevent and reduce youth tobacco use should be a focus of public health efforts to reduce overall tobacco use. As states develop tobacco use prevention programs, current data on tobacco use behaviors among youth and how such data change over time in response to program activities must guide program design, implementation, and evaluation. Findings from the evaluation of the youth-focused Florida Pilot Program on Tobacco Control (FPPTC), reported elsewhere12 and presented here, suggest that a comprehensive, youth-led program, incorporating multiple approaches to youth tobacco use prevention and reduction, can be successful.