Implications for Isoform-selective Inhibitor Design Derived from the Binding Mode of Bulky Isothioureas to the Heme Domain of Endothelial Nitric-oxide Synthase

This publication has 29 references indexed in Scilit:

• Formation of a Pterin Radical in the Reaction of the Heme Domain of Inducible Nitric Oxide Synthase with Oxygen
  Biochemistry, 1999
• Mammalian nitric oxide synthases
  Published by Elsevier ,1999
• Crystal Structure of Constitutive Endothelial Nitric Oxide Synthase: A Paradigm for Pterin Function Involving a Novel Metal Center
  Cell, 1998
• Reaction of Neuronal Nitric-oxide Synthase with Oxygen at Low Temperature
  Published by Elsevier ,1998
• Neuronal nitric oxide synthase, a modular enzyme formed by convergent evolution: structure studies of a cysteine thiolate‐liganded heme protein that hydroxylates L‐arginine to produce NO as a cellular signal
  The FASEB Journal, 1996
• Nitric Oxide: A New Paradigm for Second Messengers
  Journal of Medicinal Chemistry, 1995
• Nitric Oxide Synthases: Properties and Catalytic Mechanism
  Annual Review of Physiology, 1995
• Calmodulin is a subunit of nitric oxide synthase from macrophages.
  The Journal of Experimental Medicine, 1992
• Biosynthesis of endothelium-derived relaxing factor: A cytosolic enzyme in porcine aortic endothelial cells Ca2+-dependently converts L-arginine into an activator of soluble guanylyl cyclase
  Biochemical and Biophysical Research Communications, 1989
• Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase.
  Proceedings of the National Academy of Sciences, 1989