Recycling of a perfluoroalkylated BINOL ligand using fluorous solid-phase extraction
- 25 February 2005
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Green Chemistry
- Vol. 7 (5) , 316-320
- https://doi.org/10.1039/b418039a
Abstract
After the asymmetric addition of allyltri-n-butyltin to benzaldehyde, a perfluoroalkylated BINOL-Sn complex was separated from the organic product using fluorous reverse phase silica gel. The lightly fluorinated ligand was then recovered by hydrolysis of the Rf6-BINOL-Sn complex with dilute hydrochloric acid and was reused three times without loss of activity or enantioselectivity.Keywords
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