Depression and Sickle Cell Anemia

Abstract
Very few reports of depression occurring with sickle cell anemia have been documented. We have reported three cases of depression in patients with sickle cell anemia that were referred over a relatively brief period, and that were successfully treated with antidepressant medication and family therapy. We examined possible mechanisms of depression, and concluded that depression may accompany sickle cell anemia more commonly than previously suspected.

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