Immunoassay of Plasma Growth Hormone in Cats Following Fasting and Administration of Insulin, Arginine, 2-Deoxyglucose and Hypothalamic Extract
- 1 February 1971
- journal article
- other
- Published by The Endocrine Society in Endocrinology
- Vol. 88 (2) , 359-366
- https://doi.org/10.1210/endo-88-2-359
Abstract
Plasma GH levels were measured in unanesthetized cats following various procedures known to stimulate GH secretion in man. The radioimmunoassay system used in the present study could measure plasma GH in concentrations between 4 and 100 ng/ml. Antiserum to cat GH cross-reacted with purified rat and rabbit GH but did not bind GH or ACTH from man or LH and TSH from sheep. Similarly, pituitary extracts from cat, rat, rabbit and dog inhibited binding of labeled cat GH to its antibody, whereas human and monkey pituitary extracts had little effect. Immunoreactive plasma GH levels in cats were not changed by insulin hypoglycemia, fasting, intravenous glucose, arginine infusion or by injection of sheep hypothalamic extract. Plasma GH rose significantly (p Endocrinology88: 359, 1971)Keywords
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