Hydration and the lamellar to hexagonal(II) phase transition of phosphatidylethanolamine
- 18 November 1986
- journal article
- research article
- Published by American Chemical Society (ACS) in Biochemistry
- Vol. 25 (23) , 7518-7522
- https://doi.org/10.1021/bi00371a039
Abstract
The effects of chaotropic agents on the lamellar to hexagonal II phase transition of soy phosphatidylethanolamine were examined. Guanidine hydrochloride, urea, and NaSCN were used as chaotropic agents. In each case, the lamellar phase was stabilized by the presence of the chaotropic agent. In the case of NaSCN, the temperature of the lamellar to hexagonal phase transition of soy phosphatidylethanolamine was increased by more than 60.degree. C. Guanidine hydrochloride was capable of substantially reducing the aggregation of phosphatidylethanolamine vesicles. These data lead to a thermodynamic understanding of the lamellar to hexagonal phase transition.This publication has 1 reference indexed in Scilit:
- Hydrogen-bonding of the ester carbonyls in phosphatidylcholine bilayersBiochemical and Biophysical Research Communications, 1976