Transgenic mice overexpressing the neurotrophic factor S-100β show neuronal cytoskeletal and behavioral signs of altered aging processes: implications for Alzheimer's disease and Down's syndrome
Open Access
- 1 November 1997
- journal article
- Published by Elsevier in Brain Research
- Vol. 776 (1-2) , 51-60
- https://doi.org/10.1016/s0006-8993(97)01002-0
Abstract
No abstract availableKeywords
This publication has 30 references indexed in Scilit:
- Overexpression of a calcium-binding protein, S100 beta, in astrocytes alters synaptic plasticity and impairs spatial learning in transgenic mice.Learning & Memory, 1995
- An Increase in Phosphorylation of Microtubule‐associated Protein 2 Accompanies Dendrite Extension During the Differentiation of Cultured Hippocampal NeuronesEuropean Journal of Biochemistry, 1995
- S100β protein expression in Alzheimer disease: Potential role in the pathogenesis of neuritic plaquesJournal of Neuroscience Research, 1994
- Dendritic and histochemical development and ageing in patients with Down's syndromeJournal of Intellectual Disability Research, 1994
- Possible role of S-100 in glia—Neuronal signalling involved in activity-dependent plasticity in the developing mammalian cortexJournal of Chemical Neuroanatomy, 1993
- Developmental Changes of S-100 Protein and Glial Fibrillary Acidic Protein in the Brain in Down SyndromeExperimental Neurology, 1993
- S‐100β and insulin‐like growth factor‐II differentially regulate growth of developing serotonin and dopamine neurons in vitroJournal of Neuroscience Research, 1992
- The roles of microtubule-associated proteins in brain morphogenesis: a reviewBrain Research Reviews, 1990
- Embryonic MAP2 lacks the cross-linking sidearm sequences and dendritic targeting signal of adult MAP2Nature, 1989
- A membrane phosphoprotein associated with neural development, axonal regeneration, phospholipid metabolism, and synaptic plasticityTrends in Neurosciences, 1987