DL and the dimensions and functional capacities of the O2 transport system in humans.

Publisher Website
Google Scholar
Abstract
Pulmonary diffusing capacity was measured during exercise, with steady-state technique in 10 healthy young men and women and related to a number of measures of body size, static dimensions, and functional capacities of the lungs and of the cardiovascular system. The static dimensions of the lungs were determined as total lung capacity and its subdivisions. The functional capacity of the lungs was measured as the maximal voluntary ventilation and ventilation during determination of maximal O2 uptake. The static dimensions of the cardiovascular system were determined by the total hemoglobin, blood volume, stroke volume of the heart, and hemoglobin concentration. The functional capacity of the cardiovascular system was measured as the maximal cardiac output and maximal heart rate. DLCO [diffusion capacity of the lungs for CO2] was significantly correlated to all these variables. The highest correlation coefficient was to total hemoglobin. Elimination of the influence of hemoglobin concentration eliminated the difference between sexes. The results demonstrate that a high diffusiong capacity is accompanied by a high aerobic capacity, large lungs with a large ventilatory capacity, and a large cardiovascular system with a large maximal cardiac output.

This publication has 1 reference indexed in Scilit: