Up-regulated delta 9-desaturase gene expression by hypolipidemic peroxisome-proliferating fatty acids results in increased oleic acid content in liver and VLDL: accumulation of a delta 9-desaturated metabolite of tetradecylthioacetic acid
Open Access
- 1 March 1997
- journal article
- Published by Elsevier in Journal of Lipid Research
- Vol. 38 (3) , 554-563
- https://doi.org/10.1016/s0022-2275(20)37263-1
Abstract
No abstract availableKeywords
This publication has 23 references indexed in Scilit:
- Long-term effect of tetradecylthioacetic acid: a study on plasma lipid profile and fatty acid composition and oxidation in different rat organsBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1996
- Clofibrate treatment increases stearoyl-CoA desaturase mRNA level and enzyme activity in mouse liverBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1995
- Hepatic Fatty Acid Metabolism as a Determinant of Plasma and Liver Triacylglycerol Levels. Studies on Tetradecylthioacetic and Tetradecylthiopropionic AcidsEuropean Journal of Biochemistry, 1995
- Transcriptional Control of the Stearoyl-CoA Desaturase-1 Gene by Polyunsaturated Fatty Acids1Biochemical and Biophysical Research Communications, 1994
- Impact of cytochrome P450 system on lipoprotein metabolism. Effect of abnormal fatty acids (3-thia fatty acids)Pharmacology & Therapeutics, 1994
- Coordinate induction of hepatic fatty acyl-CoA oxidase and P4504A1 in rat after activation of the peroxisome proliferator-activated receptor (PPAR) by sulphur-substituted fatty acid analoguesXenobiotica, 1994
- Structural and metabolic requirements for activators of the peroxisome proliferator-activated receptorBiochemical Pharmacology, 1993
- Effect of 3-thiadicarboxylic acid on lipid metabolism in experimental nephrosis.Arteriosclerosis and Thrombosis: A Journal of Vascular Biology, 1993
- Fatty acid metabolism in liver of rats treated with hypolipidemic sulphur-substituted fatty acid analoguesBiochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1990
- Alkylthio acetic acids (3-thia fatty acids)—A new group of non-β-oxidizable peroxisome-inducing fatty acid analogues—II. Dose-response studies on hepatic peroxisomal- and mitochondrial changes and long-chain fatty acid metabolizing enzymes in ratsBiochemical Pharmacology, 1989