SLAM Family Receptors Regulate Immunity with and without SAP-related Adaptors
Open Access
- 3 May 2004
- journal article
- review article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 199 (9) , 1175-1178
- https://doi.org/10.1084/jem.20040588
Abstract
Two papers describing mice deficient in signaling lymphocyte activation molecule and 2B4 represent the first accounts of immune phenotypes in animals lacking members of the SLAM family of receptors. The findings provide definitive evidence of the importance of SLAM-related receptors in the regulation of T cell, macrophage, and natural killer cell functions.Keywords
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