Long-Term Follow-up Study of Penicillin-Treated Subacute Bacterial Endocarditis

Abstract
SINCE 1944, when penicillin became available in quantity, subacute bacterial endocarditis has moved from the category of an almost uniformly fatal disorder to the ranks of curable disease. Among the many well documented papers1 2 3 4 5 6 7 8 9 10 11 12 13 14 supporting the efficacy of treatment is an earlier report from this clinic.15 During the past five years, the original group of patients described has been considerably augmented. It is the purpose of this paper to report on the altered clinical pattern seen in these patients since the advent of penicillin therapy, and the effect of this therapy on long-term results.Clinical MaterialFrom 1944 through 1947, . . .