The Treatment of Subacute Bacterial Endocarditis with Penicillin in Peanut Oil and Beeswax

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Abstract
THE apparent curability of subacute bacterial endocarditis with penicillin has been unequivocally established within the last two years.1 The essentials of successful therapeusis consist of treatment with massive daily doses of penicillin for a month or longer, the actual amount given daily depending on the resistance of the infecting organism to penicillin and on the serum penicillin concentrations attained. Supplementation of the penicillin with heparin, as first advocated by Loewe and his associates,2 has proved unnecessary in our experience3 as well as that of others,1 and the dispensability of this costly and usually troublesome adjuvant has gratifyingly simplified the therapeutic . . .

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