Sterility Induced in Boll Weevils by Alkylating Agents Administered in an Adult Diet12

Abstract
The chemosterilant activity of 4 alkylating agents to adult Anthonomus grandis Boheman was investigated. A diet containing 0.1% busulfan (1, 4-butanediol dimethane-sulfonate or ENT 25012) and fed for 6 days produced sterility in both sexes in 5 out of 7 tests. Busulfan 0.2% for 6 days and 0.4% for 4 days generally were effective against both sexes, but mortality was high in the male. Although ENT 61168 (diethylene glycol dimethanesulfonate) was ineffective against the male, this compound generally sterilized the females at either 0.4% for 4 and 6 days or 0.8% for 4 days. ENT 51904 (1, 3-propanediol dimethanesulfonate) was ineffective against the male, but all regimes produced sterility in the female. Apholate produced sterility in both sexes only when accompanied by excessive mortality.

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