The Inheritance of the Exstrophy-Epispadias Complex
- 1 August 1984
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Urology
- Vol. 132 (2) , 308-310
- https://doi.org/10.1016/s0022-5347(17)49605-4
Abstract
The inheritance pattern of the exstrophy-epispadias complex was investigated by a combined literature review and a survey of the personal experience of pediatric urologists in North and South America, and Europe. Bladder exstrophy recurred in only 9 of approximately 2,500 families (1 in 275) with bladder exstrophy or complete epispadias. The recurrence of the exstrophy-epispadias complex in offspring of parents with bladder exstrophy or complete epispadias has never been described previously. We identified 215 offspring produced by parents with bladder exstrophy or epispadias, and bladder exstrophy was inherited in 3 of the offspring (1 in 70 live births). The recurrence of bladder exstrophy in offspring of parents with the exstrophy-epispadias complex is greater than previously assumed.This publication has 12 references indexed in Scilit:
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