Transient Late Magnetic Resonance Imaging Changes Suggesting Progression of Brain Stem Glioma: Implications for Entry Criteria for Phase II Trials
- 1 August 1988
- journal article
- case report
- Published by Wolters Kluwer Health in Neurosurgery
- Vol. 23 (2) , 248-253
- https://doi.org/10.1227/00006123-198808000-00024
Abstract
An 8-year-old boy was treated with irradiation (66 Gy) for a brain stem glioma. Five months after the completion of radiotherapy, magnetic resonance imaging demonstrated apparent tumor progression despite the patient's neurological improvement. The child continued to improve, with subsequent radiographic evidence of tumor regression, without additional therapeutic intervention. The evaluations of response and recurrence of brain tumors as well as entry criteria for Phase II studies are discussed.Keywords
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