Colorectal cancer screening: sifting through the evidence.

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Abstract
Worldwide, colorectal cancer is the third most common form of cancer in men and the second in women, with approximately 875 000 new cases diagnosed annually with 570 000 deaths ( 1 ). In the United States, colorectal cancer is the fourth most common cancer and the second leading cause of cancer death. Annually, approximately 129 000 new cases of colorectal cancer are diagnosed, with 57 000 associated deaths ( 2 ). Early detection through effective screening is one of the strategies to decrease mortality from colorectal cancer.