Rhodopeptins (Mer-N1033), Novel Cyclic Tetrapeptides with Antifungal Activity from Rhodococcus sp. I. Taxonomy, Fermentation, Isolation, Physico-chemical Properties and Biological Activities.
Open Access
- 1 January 1999
- journal article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 52 (8) , 695-699
- https://doi.org/10.7164/antibiotics.52.695
Abstract
Five novel cyclic tetrapeptides, named rhodopeptin Cl, C2, C3, C4 and B5, were isolated from a strain named Rhodococcus sp. Mer-N1033. They are a novel type of cyclic tetrapeptide composed of a β-amino acid and three usual α-amino acids. Rhodopeptins show high in vitro antifungal activity against Candida albicans and Cryptococcus neoformans, whereas they show no activity against bacteria.Keywords
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