DNA fingerprinting by hybridisation to oligonucleotide arrays
- 1 January 1995
- journal article
- review article
- Published by Wiley in Electrophoresis
- Vol. 16 (1) , 1539-1542
- https://doi.org/10.1002/elps.11501601256
Abstract
Most methods for analysing variation in DNA sequences rely on gel electrophoresis, a method which is difficult to automate and to quantify. Hybridisation to oligonucleotides bound to a solid surface offers alternatives, with the advantage that they can be more readily automated and lend themselves to powerful statistical analytical procedures. In this paper, we discuss a number of different ways in which oligonucleotide arrays could be used for DNA typing for applications in forensic science.Keywords
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