Abnormalities of Cyclic Adenosine Monophosphate Signaling in Platelets From Untreated Patients With Bipolar Disorder
Open Access
- 1 March 1999
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of General Psychiatry
- Vol. 56 (3) , 248-253
- https://doi.org/10.1001/archpsyc.56.3.248
Abstract
BIPOLAR DISORDER is a common illness affecting approximately 1% of the population.1 The biochemical mechanisms underlying the pathogenesis of this disorder remain to be clearly established. In recent years, however, numerous studies2-12 have reported abnormalities in components of cyclic adenosine monophosphate (cAMP) signaling such as G proteins in postmortem brain and peripheral cells of patients with bipolar disorder.Keywords
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