Loss of Two Steroid 11β-Hydroxylating Components in a Rat Adrenocortical Carcinoma2
- 1 November 1964
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 33 (5) , 849-854
- https://doi.org/10.1093/jnci/33.5.849
Abstract
Examination of the Snell homologously transferred rat Adrenocarcinoma 494 indicated a loss of two components (F-40 and F-80) associated with steroid 11β-hydroxylation in normal adrenal tissue. The tumor retained the mechanisms associated with 21-hydroxylation of progesterone and C-5 isomerization and C-3 oxidation of pregnenolone.Keywords
This publication has 3 references indexed in Scilit:
- Enzymic Steroid Conversions in a MasculinovoblastomaJournal of Clinical Endocrinology & Metabolism, 1962
- PATHOPHYSIOLOGY OF CONGENITAL ADRENAL HYPERPLASIA1960
- Variations in Histologic Pattern and Functional Effects of a Transplantable Adrenal Cortical Carcinoma in Intact, Hypophysectomized, and Newborn RatsJNCI Journal of the National Cancer Institute, 1959