Inhibition of the ATP‐driven proton pump in RPE lysosomes by the major lipofuscin fluorophore A2‐E may contribute to the pathogenesis of age‐related macular degeneration
Open Access
- 8 January 2004
- journal article
- fj express-summaries
- Published by Wiley in The FASEB Journal
- Vol. 18 (3) , 562-564
- https://doi.org/10.1096/fj.03-0289fje
Abstract
Lipofuscin accumulation in the retinal pigment epithelium (RPE) is associated with various blinding retinal diseases, including age-related macular degeneration (AMD). The major lipofuscin fluorophor...Keywords
Funding Information
- Deutsche Forschungsgemeinschaft (SPP 1088)
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