A laser light scattering in situ system for counting aggregates in blood platelet aggregation

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Abstract
A novel system has been developed to evaluate biochemically induced blood platelet aggregation by means of a particle counting technique that uses light scattering. Variations in the particle size and concentration were measured by detecting the scattered light intensity and the number of particles, respectively, passing through a laser beam. The system is capable of performing sensitive, in situ continuous measurements of platelet aggregation by counting and sizing of aggregates.