Esophageal Prostaglandins in Guinea Pigs and Rats
- 1 January 1990
- journal article
- research article
- Published by S. Karger AG in Cells Tissues Organs
- Vol. 139 (1) , 66-69
- https://doi.org/10.1159/000146980
Abstract
The synthesis of prostaglandins (PGs) in the mucosa of the esophagus is studied in 20 albinotic adult guinea pigs and rats using the radioimmunoassay method. Both species investigated synthesize five PGs. The PG synthesis activity in the guinea pig’s esophagus is higher than that in the rat’s. PGE2 and PGF2α might be involved in the regulation of lower esophagus sphincter pressure.Keywords
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