Long-term feeding of sodium saccharin to nonhuman primates: implications for urinary tract cancer.
Open Access
- 7 January 1998
- journal article
- research article
- Published by Oxford University Press (OUP) in JNCI Journal of the National Cancer Institute
- Vol. 90 (1) , 19-25
- https://doi.org/10.1093/jnci/90.1.19
Abstract
It was observed in the early 1970s that saccharin produced bladder cancer in rats. However, it has been unclear whether sodium saccharin when consumed by humans poses a substantial carcinogenic hazard. Numerous epidemiologic studies have not shown any evidence of increased urothelial proliferation associated with ingestion of sodium saccharin.Keywords
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