Model studies directed toward the total synthesis of 14-membered cyclopeptide alkaloids: synthesis of prolyl peptides via a four-component condensation
- 1 January 1989
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 5,p. 857-865
- https://doi.org/10.1039/p19890000857
Abstract
The general applicability of a four-component condensation for the formation of N-acyl-β-aryloxyprolines has been demonstrated in several model studies. The relative stereochemistry of the diastereoisomers obtained has been assigned from 1H n.m.r. studies, and confirmed by an X-ray analysis of one of the stereoisomers.Keywords
This publication has 2 references indexed in Scilit:
- Synthesis of dihydromauritine A, a reduced cyclopeptide alkaloidThe Journal of Organic Chemistry, 1984
- t-BUTYL HYPOCHLORITEOrganic Syntheses, 1969