Effects of X-irradiation on the proliferation of cells in peripheral nerve during allerian degeneration in the rat

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Abstract
The changes in nuclear populations in the rat sciatic nerve after crush injury were determined, both in normal animals and at various times following X-irradiation with doses from 200 to 2000 rads. Definite changes are detectable at 7 days after crush following 200 rads and these increase with increasing irradiation doses. At 14 days the populations after 200 and 500 rads return to normal levels. After 1000 and 2000 rads a marked difference from normal exists. The effects persist substantially unchanged for at least 6 months.